Job summary
- Main area
- Genomics
- Grade
- Band 8a
- Contract
- Fixed term: 2 years (lasting until 31st March 2028)
- Hours
- Full time - 37.5 hours per week
- Job ref
- 271-GEN-7780281
- Employer
- Great Ormond Street Hospital for Children NHS Foundation Trust
- Employer type
- NHS
- Site
- Barclay House, Great Ormond Street Hospital
- Town
- London
- Salary
- £64,156 - £71,148 per annum inclusive
- Salary period
- Yearly
- Closing
- 12/04/2026 23:59
Employer heading
Senior Translational Scientist
Band 8a
Job overview
Come and join our research team and help us develop genetic services Band 8a Senior Translational Scientist required
Do you want to help us transform NHS prenatal diagnostic and genetic
services? We are seeking a skilled and enthusiastic Scientist funded by the
Great Ormond Street Biomedical Research Centre to join our team based in the NHS North Thames Genomic Laboratory Hub at Great Ormond Street Hospital. Our team is delivering transformation in patient care by using circulating cell free DNA to develop new approaches for safe prenatal diagnosis, pipelines for rapid, comprehensive diagnosis of paediatric conditions such as early onset epilepsy using genome sequencing and utilising long read sequencing technologies to transform clinical services. In addition, as one of the biggest recruiters to the 100,000 Genomes Project, we are now exploring new approaches to identify causative variants in unsolved cases.
Main duties of the job
If you are committed to contributing to a team delivering excellence in
research into genetics and would like to gain experience in translational
research this is definitely the post for you. This Band 8a post is available
immediately, funded until 31st March 2028 in the first instance, with a
possibility of extension if we are successful in renewing the BRC. You will be joining an enthusiastic, friendly, motivated multidisciplinary research team working closely with the Clinical Scientific and Bioinformatics team. This is an ideal opportunity to contribute to the translation of research into clinical practice for the benefit of our patients. It’s a great chance to experience working in an expert translational research environment based in a thriving Genomic Laboratory Hub closely affiliated to the academic environment of the UCL GOS Institute of Child Health. This post is also suitable for experienced Clinical scientists wanting to broaden their horizons and undertake a secondment to gain experience of translational research. Hybrid working is supported, however, after the probation period a minimum of 40% on site working is required.
Working for our organisation
We are keen to make our workforce as diverse as the communities we serve, and we hope to attract applications from underrepresented groups, including people with Black, Asian and Minority Ethnic heritage, people with a disability, and people from LGBTQ+ communities. By growing an ever more diverse workforce, we’ll have a greater range of perspectives and knowledge, meaning that we can provide the children and young people at our hospital with even better care.
Our hospital is committed to creating an environment that is open and inclusive. Our staff are encouraged to engage with colleagues through the following networks: REACH (Race, Ethnicity and Cultural Heritage) ENABLED (Enhancing Abilities & Leveraging Disabilities Network), PRIDE and Women’s networks; all of which are sponsored by a member of our Executive Management Team.
We want to ensure that all of our people, regardless of their background, are seen and heard. We want to attract applicants that share our commitment to inclusion and that understand diversity is a strength that is embraced and valued.
Detailed job description and main responsibilities
The full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience and knowledge required. For both documents please view the attachment/s below.
Person specification
GOSH Culture and Values
Essential criteria
- Our Always Values
- Knowledge and Understanding of diverse backgrounds and perspectives.
- Understanding of Diversity and Inclusion challenges in the workplace.
- Demonstrable contribution to advancing Equality, Diversity and Inclusion in the Workplace
- Ability to work on site when required
Academic/Professional qualification/Training
Essential criteria
- PhD related to genomics or equivalent experience
- 1st or 2nd class honours degree in genetics or a relevant biological subject
- State Registered Clinical Scientist (HCPC)
Desirable criteria
- Commitment to RCPath Fellowship
Experience/Knowledge
Essential criteria
- At least 5 years postgraduate experience in a molecular genetics laboratory
- Extensive & comprehensive knowledge of molecular genetics and the development / translation of methods / techniques
- Experience of research in genetics
- Up to date knowledge of scientific literature and best practice guidance relating to molecular genetic tests
Desirable criteria
- Experience of staff management
- Track record of scientific first author publications
- Evidence of supervising/training other staff
- Knowledge of appropriate Quality Management and Audit regulations and requirements
- Up to date knowledge of cell free DNA
- Up to date knowledge of long read sequencing techniques
- Knowledge of appropriate Health and Safety regulations and requirements
Skills/Abilities
Essential criteria
- Skilled in the use of genetics techniques including NGS technologies
- Evidence of excellent inter-personal communication skills
- Excellent organisational and time management skills with ability to prioritise tasks effectively
- Able to establish and validate new techniques / tests including ability to troubleshoot. Willing to adapt to changes in methodology
- Ability to develop and maintain excellent communication and working relationships
- Proactive and innovative approach to service improvement and delivery
- Computer literate, including use of DNA/Genetic databases, analytical software, variant classification
- Ability to collate, write, publish and present research findings
Desirable criteria
- Familiar with Genetic analysers, robotics
Employer certification / accreditation badges
Applicant requirements
You must have appropriate UK professional registration.
The postholder will have regular contact with vulnerable people and as such this post is subject to the Rehabilitation of Offenders Act 1974 (Exceptions) Order 1975 (Amendment) (England and Wales) Order 2020 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service to check for any previous criminal convictions.
Application numbers
Documents to download
Further details / informal visits contact
- Name
- Natalie Chandler
- Job title
- Principal Clinical Scientist
- Email address
- [email protected]
- Additional information
For enquiries or an informal visit please contact Natalie Chandler
[email protected] or Lyn Chitty – [email protected]
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