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Job summary

Main area
Trial Manager / Clinical Research Practitioner II
Grade
NHS AfC: Band 6
Contract
12 months (Fixed term: 12 months)
Hours
Part time - 19 hours per week
Job ref
196-RD315
Employer
Guy's and St Thomas' NHS Foundation Trust
Employer type
NHS
Site
Burrell St Sexual Health Clinic
Town
London
Salary
£44,806 - £53,134 per annum inc HCA
Salary period
Yearly
Closing
29/06/2025 23:59
Interview date
09/07/2025

Employer heading

Guy's and St Thomas' NHS Foundation Trust logo

Trial Manager / Clinical Research Practitioner II

NHS AfC: Band 6

Guy’s and St Thomas’ is among the UK’s busiest and most successful NHS foundation trusts. We provide a full range of hospital and community services for people in south London and as well as specialist care for patients from further afield including cancer, renal, orthopaedic, respiratory and cardiovascular services.

Guy’s is home to the largest dental school in Europe and a £160 million Cancer Centre opened in 2016. As part of our commitment to provide care closer to home, in 2017 we also opened a cancer centre and a kidney treatment centre at Queen Mary’s Hospital in Sidcup. St Thomas’ has one of the largest critical care units in the UK and one of the busiest emergency departments in London. It is also home to Evelina London Children’s Hospital.

Evelina London cares for local children in Lambeth and Southwark and provides specialist services across south east England including cardiac, renal and critical care services. We lead a number of specialist service networks aiming to ensure children are treated locally where possible, but have access to specialist expertise when they need it. Our community services include health visiting, school nursing and support for families of children with long-term conditions. 

Our adult community services teams deliver care at the heart of the local communities we serve, working in partnership with GPs, local authorities and other healthcare and voluntary sector organisations. Working with our partners in Lambeth and Southwark, we are focusing on new ways of working to improve care for local patients.

In February 2021 the Royal Brompton and Harefield joined Guy’s and St Thomas’ NHS Foundation Trust, bringing together world-leading expertise in the care and research of heart and lung disease. Our merger provides a once in a generation opportunity to build a lasting, world-renowned heart and lung centre, providing the highest quality care for patients and conducting world-leading research.

We have a reputation for clinical excellence and high quality teaching and research. We are part of King’s Health Partners, one of eight accredited UK academic health sciences centres. In partnership with King’s College London we have dedicated clinical research facilities including an MHRA accredited Phase I clinical trials unit.

Patients are at the heart of everything we do and we pride ourselves on ensuring the best possible patient experience as well as safe, high quality care. We are proud to have one of the lowest mortality rates in the NHS. Following a comprehensive Care Quality Commission (CQC) inspection in 2019 we maintained our overall rating of ‘good’. Our adult community services achieved a rating of ‘outstanding’.

The commitment of our 23,500 staff is key to our success. We are one of the largest local employers and we aim to develop and support all our staff so they are able to deliver high quality, safe and efficient care. The 2019 NHS staff survey results show that we have one of the most engaged and motivated workforces in the NHS. We know this has a positive impact on the care provided to our patients.

We have one of the most ambitious capital investment programmes anywhere in the NHS.



Job overview

We are seeking a dynamic and experienced Clinical Research Practitioner to manage the LISA study, a clinical trial investigating treatments for bacterial vaginosis and candida. This exciting study compares standard oral treatments to vaginal lactoferrin and includes both quantitative and qualitative components. The successful candidate will lead on all trial management activities including recruitment, data quality, participant follow-up, and sample handling, ensuring adherence to ICH-GCP standards.

This is a part-time position based across two main research sites: Burrell St Sexual Health Clinic and Curran General Practice in Clapham.

Main duties of the job

 

  • Manage day-to-day operations of the LISA trial including recruitment, randomisation, consent, and follow-up of study participants.

  • Conduct qualitative interviews with participants to support the study's mixed-methods design.

  • Organise and lead Trial Management Group and Trial Steering Group meetings, presenting progress and recruitment updates.

  • Liaise with Clinical Trials Unit to manage study database and randomisation system.

  • Coordinate collaboration with internal departments (e.g., R&D, Pharmacy, Labs) and external bodies (e.g., IMP manufacturers).

  • Develop and maintain trial-specific documentation, SOPs, and the Trial Master File (TMF).

  • Organise and ensure quality control of participant sample packs and sample tracking, analysis, and storage.

  • Support protocol amendment processes and represent the trial at conferences and stakeholder meetings.

Working for our organisation

You will be joining one of the UK’s most respected NHS Trusts, committed to delivering cutting-edge research that directly informs and enhances patient care. The Trust is a major centre for academic and clinical excellence and provides an inclusive, supportive environment for career development and research delivery. 

Detailed job description and main responsibilities

Clinical and Communication Responsibilities

  • Manage a caseload of participants, ensuring informed consent and compliance with trial protocols.

  • Perform clinical assessments (e.g., vitals, sample collection, urinalysis) and support biological sample preparation.

  • Report adverse events and deviations from protocol in a timely and professional manner.

  • Maintain accurate and complete participant records and liaise effectively with the clinical team.

Research and Portfolio Management

  • Assist in study setup, protocol reviews, and R&D submissions.

  • Maintain accurate CRFs and ensure timely resolution of data queries.

  • Monitor and report recruitment metrics, support study accrual efforts, and liaise with sponsors.

  • Ensure all trial documentation is archived and compliant with regulatory requirements.

Management and Leadership

  • Line manage junior research staff as required and contribute to performance appraisals.

  • Lead on policy implementation and service quality improvements.

  • Act as a role model and mentor within the research team and represent the Trust in external forums.

Education & Professional Development

  • Maintain professional development through ongoing training and reflective practice.

  • Contribute to SOP development and support educational activities across the research department.

Additional Responsibilities

  • Ensure responsible use of research equipment and resources in line with study budgets.

  • Work flexibly to meet the needs of the study, including occasional evenings or weekends.

  • Foster cross-departmental collaboration and integration of research within clinical services.

Person specification

Qualifications/ Education

Essential criteria
  • Degree in life sciences or related field or equivalent theoretical knowledge
  • Evidence of continuing professional development
  • GCP certificate
Desirable criteria
  • Registered on AHCS clinical research practitioner accredited register

Previous experience

Essential criteria
  • Significant experience in relevant clinical research delivery setting
  • Experience managing complex projects
Desirable criteria
  • Experience within speciality

Skills/Knowledge/ Ability

Essential criteria
  • Excellent communication skills and ability to deal with complex and sensitive situations
  • Ability to work autonomously and as a member of a small team, as well as part of the wider multidisciplinary team
Desirable criteria
  • Proficient with basic laboratory skills

Physical Requirements

Essential criteria
  • Willingness and ability to travel to external meetings within the context of this post
  • Able to concentrate for prolonged periods when cross-referencing medical case notes

Employer certification / accreditation badges

Timewise helps businesses to attract and develop the best talent through flexible working.Care quality commission - GoodDisability confident employer

Applicant requirements

The postholder will have access to vulnerable people in the course of their normal duties and as such this post is subject to the Rehabilitation of Offenders Act 1974 (Exceptions) Order 1975 (Amendment) (England and Wales) Order 2020 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service to check for any previous criminal convictions.

Documents to download

Apply online now

Further details / informal visits contact

Name
Amy Day
Job title
Research Manager
Email address
[email protected]
Additional information

Due to volume of applications, your query may only be responded to if you are shortlisted for interview. 

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