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Job summary

Main area
Neurology
Grade
NHS Medical & Dental: Local Appointment nodal point 3 (MT03)
Contract
Fixed term: 12 months (Limited Funding)
Hours
Full time - 40 hours per week (There is no out-of-hours commitment with this role.)
Job ref
309-UCLH-8071
Employer
University College London Hospitals NHS Foundation Trust
Employer type
NHS
Site
National Hospital for Neurology & Neurosurgery
Town
London
Salary
£54,499 per annum + London Weighting
Salary period
Yearly
Closing
05/07/2026 23:59

Employer heading

University College London Hospitals NHS Foundation Trust logo

Clinical Research Fellow

NHS Medical & Dental: Local Appointment nodal point 3 (MT03)

The use of AI is monitored and if applicants have used it, then they are required to declare this in their supporting statement.

Artificial intelligence (AI) is a set of technology that can perform various tasks that typically required human intelligence. Your application is your opportunity to demonstrate to us how you meet the requirements of the role.

We recognise that AI tools can support accessibility, equity and confidence for applicants. However, it’s important that examples and responses genuinely reflect your own experience and abilities, as these will be explored further during the selection process. AI must not be used to provide misleading or false information during any stage of the application journey.

Further guidance can be found in the NLPSS Applicant Toolkit https://royalfree.pagetiger.com/cuuomnr/1.

University College London Hospitals NHS Foundation Trust is committed to fair and transparent recruitment and requires applicants to provide accurate information, as misleading details may affect their application or employment and may be verified in line with the Fraud Act 2006. For further information please visit https://royalfree.pagetiger.com/cuuomnr/1.

Job overview

Clinical Research Fellow– UCL/UCLH Institute of Neurology, Ataxia Centre
Applications are invited for a Clinical Research Fellow in the Ataxia Centre, UCL/UCLH Department of Neuroscience and Neurogenetics, UCL Institute of Neurology, under the supervision of Prof Paola Giunti.

The post offers an exciting opportunity to gain experience of translational research as part of an internationally recognised multi-disciplinary team.

Main duties of the job

The postholder will be an essential member of the research team at the Ataxia Centre, providing clinical and research input into the Centre’s research programme into Ataxia and will work closely with the Principal Investigators (PIs), Clinical Research Fellows and Clinical Trials nurses. Their primary role will be as sub-investigator in clinical drug trial: A phase 1/2a, open-label trial to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple ascending doses of intrathecally administered VO659 in participants with spinocerebellar ataxia types 1, 3. assessing the safety of this novel Antisense oligonucleotide(ASO) treatment in patients with these rare diseases. He/she will also have the opportunity to participate in current basic and observational research including longitudinal studies of dominant and recessive ataxias and at-risk groups and healthy volunteers to identify reliable biomarkers of disease and develop new therapeutic targets.

The postholder will gain extensive experience in the set up and execution of clinical trials and laboratory based / translational research. They will also be involved in the clinical activity of the Ataxia clinics and the multidisciplinary meeting.

Applicants should have a medical degree and eligible for full registration with the GMC at time of appointment and hold a current licence to practise and have previous experience in neurology, or general medicine and excellent skill in performing lumbar puncture

Working for our organisation

University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services, to people from the local area, from throughout the United Kingdom and overseas. Our vision is to deliver top-quality patient care, excellent education, and world-class research.

We provide first-class acute and specialist services across eight sites:
• University College Hospital (incorporating the Elizabeth Garrett Anderson Wing)
• National Hospital for Neurology and Neurosurgery
• Royal National ENT and Eastman Dental Hospitals
• University College Hospital Grafton Way Building
• Royal London Hospital for Integrated Medicine
• University College Hospital Macmillan Cancer Centre
• The Hospital for Tropical Diseases
• University College Hospital at Westmoreland Street

We are dedicated to the diagnosis and treatment of many complex illnesses. UCLH specialises in women’s health and the treatment of cancer, infection, neurological, gastrointestinal and oral disease. It has world class support services including critical care, imaging, nuclear medicine and pathology.

We are committed to sustainability and have pledged to become a carbon net zero health service, embedding sustainable practice throughout UCLH. We have set an ambitious target of net zero for our direct emissions by 2031 and indirect emissions by 2040.

Detailed job description and main responsibilities

For the full Person Specification and more information regarding the main responsibilities of this role, please refer to the attached Job Description.

Please note, due to anticipated high volumes of applications, this vacancy may close earlier than the listed closing date. You are advised not to delay submitting your completed application

The successful candidate will have good inter-personal skills, the ability to work co-operatively in a multidisciplinary setting and the ability to demonstrate a record of academic clinical excellence.
Please note that if you have not heard from us within 3 weeks of the closing date of the advert to assume that you have not been shortlisted on this occasion.

Come and be a part of the best NHS trust in England to work for, according to our staff*

* UCLH top trust to work at in England - In the most recent NHS staff survey UCLH had the highest percentage of staff who said they would recommend us as a place to work, out of all general acute or acute/community NHS trusts in England – for the third year in a row.

UCLH recognises the benefits of flexible working for staff – To find out more, visit: Flexible working. 

To discover more about what makes UCLH a great place to work, visit: Why Choose UCLH?

Person specification

Knowledge and Qualifications

Essential criteria
  • Educated to degree level (Medical Degree)
  • Eligible for full registration with the GMC , eligible to apply for GMC Specialist Register, at time of appointment and hold a current licence to practise.
  • MRCP, or equivalent
  • Experience in paediatrics, neurology, or clinical genetics
Desirable criteria
  • Proven Knowledge of GPC guidelines
  • Completed/ working towards degree in the speciality or related field

Experience

Essential criteria
  • Clinical research experience/ understanding of research methodology
  • Experience of pediatrics’, neurology and/ or clinical genetics
  • Experience in delivering evidence-based practice
  • Experience of explaining complex concepts to patients in a clear and simplified manner with a very high level of consideration &care for patients, their careers and families
  • Experience of formal/informal teaching of patients and staff
  • Experience of acting as a patient advocate
Desirable criteria
  • Experience of working in the NHS
  • Experience of working with patients (children /adults) with neurodegenerative disorders

Skills and Abilities

Essential criteria
  • Previous experience in audit and evaluation
  • Ability to work under own initiative
  • Able to work autonomously with supervision
  • Able to work across organisational and professional boundaries
Desirable criteria
  • Experience of formal/informal teaching of patients and staff
  • Experience of acting as a patient advocate

Values

Essential criteria
  • Demonstrate ability to meet Trust Values of safety, kindness, teamwork and improving

Communication

Essential criteria
  • Computer literacy
  • Proven ability to communicate effectively in writing
  • Proven ability to communicate verbally
  • Good inter -personal skills with an ability to work co -operatively in a multidisciplinary setting.
Desirable criteria
  • Medical and scientific writing skills
  • Aptitude for data analysis

Personal and People Development

Essential criteria
  • Takes responsibility for own personal development plan

Employer certification / accreditation badges

London Healthy workplaceNo smoking policyLondon Living Wage is a voluntary commitment made by employers, who can become accredited with the Living Wage FoundationPositive about disabled peopleDisability confident employerStonewall equality policy. Equality and justice for lesbians, gay men, bisexual and trans people.

Applicant requirements

You must have appropriate UK professional registration.

This post is subject to the Rehabilitation of Offenders Act 1974 (Exceptions) Order 1975 (Amendment) (England and Wales) Order 2020 and it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service.

Documents to download

Apply online now

Further details / informal visits contact

Name
Abu Choudhury
Job title
Assistant General Manager
Email address
[email protected]
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